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In relevant in vitro trials, researchers administer this selective NNMT inhibitor to established drug-resistant cancer cell models to investigate

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Modulating the gut microbiota improves glucose tolerance, lipoprotein profile and atherosclerotic plaque development in ApoE-deficient mice [J]

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For instance, during sleep, the UPS facilitates the clearance of neurotoxic proteins like -amyloid, and disruptions in circadian regulation can impair this clearance, contributing to disorders such as Alzheimers disease (Xie et al., 2013