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However, without integration with behavioral medicine and lifestyle changes, these benefits will likely end when patients stop taking GLP-1 medications

Ganju and coauthors commented, Defining the role of GLP-1 RAs in Crohns disease is critical as obesity prevalence rises and integrated care models across gastroenterology, endocrinology, and obesity medicine become more essential. This study included 546 patients with CD with overweight or obesity who had initiated use of a GLP-1RA and were matched with 546 nonGLP-1RA users from the TriNetX research network

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No long-term safety trial exists for injectable use

Geerts, A