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Boursier J, Mueller O, Barret M, Machado M, Fizanne L, Araujo-Perez F, et al

It does so by reducing melanin production through the inhibition of the enzyme tyrosinase, and by converting eumelanin (dark pigment) into pheomelanin (a lighter, reddish-yellow pigment)

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Complementing the renal benefits disclosed in the SELECT trial, Apperloo et al examined the effect of semaglutide in non-diabetic obese patients with CKD