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10.1016/j.bcp.2012.02.003 Biochem

Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity

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Most peptides are fragile amino-acid chains, degraded within minutes by digestive proteases and hepatic first-pass metabolism

To precisely determine the ultrastructural localization of Gb3 in the Fabry kidney organoids, correlative light microscopy and immunogold EM with Gb3 labeling were performed