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Oxidative stress and antioxidant imbalance A fine balance between the presence of ROS and antioxidants is crucial for the proper normal functioning of the cell (Senoner et al., 2021)

Heavy metals interfere with antioxidant enzyme systems, such as glutathione peroxidase and superoxide dismutase, resulting in excessive ROS production and oxidative stress (Ghasemi et al., 2014

One of the main reasons why fibromyalgia remains hard to diagnose is that it is difficult for healthcare providers to identify the symptoms and causes of this condition

Glutathione also has a role in protein synthesis, prostaglandin and leukotriene synthesis, amino acid transport and iron metabolism

Some individuals with psoriasis show a deficiency of omega-3 fatty acids and elevations of omega-6 fatty acids, which tend to increase inflammation