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HFpEF, HFmrEF or HFrEF, respectively), we focus the review on HFpEF and HFrEF

The current standard treatment CPAP has several disadvantages, including low compliance, reliance on hospital-based clinic devices, and potential weight gain, which is not conducive to long-term disease control [24]

Cycling on and off GLP-1s (stopping treatment with planned restart) The Approach Cycling on and off GLP-1s means taking a planned break from treatment for a defined period, then re-starting on a schedule agreed in advance

To reduce the risk of an Adverse Analytical Finding, athletes and physicians should follow the minimum washout periods (see table below) to allow elimination of the glucocorticoid to a level that would not result in an Adverse Analytical Finding

doi: 10.1056/NEJMoa2032183 101 RubinoDMGreenwayFLKhalidUONeilPMRosenstockJSrrigRet al