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LL-37 and Immune Dysregulation One of the most fascinating discoveries in rosacea research involves the antimicrobial peptide LL-37

Mimetic is an agent that mimics or imitates the effects of another agent

In HandE-stained light microscopic sections the enlarged cytoplasm is eosinophilic and granular, with the granularity typically more pronounced than what is seen in livers with peroxisomal enzyme induction (Figure 7)

Ultrastructural analysis via transmission electron microscopy (TEM) further demonstrated an increase in the number and size of glucagon granules in cells from GCGR-KO mice (Fig