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In obstructive cholestasis, chronic cholestasis, and other hepatopathies, the establishment of oxidative stress is significantly increased (Wolf et al., 1997)

Tretinoin cannot be used during pregnancy or while nursing, so it may not be an option

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Dry mouth, also called xerostomia, is a condition in which the salivary glands do not produce enough saliva to keep the mouth moist or when the saliva becomes very thick and sticky