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Metformin was gavaged 4 h before the start of the IPGTT

In total, T cell subsets exhibited a long-term activation state in experimental ischemic stroke, which suggests a potential harmful role in the early phase and a protective effect in the later phase (73)

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At 600 mg/day, Coluzzi says, There are no side effects. However, double this dose is often used, which occasionally causes mild gastrointestinal irritation