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Holst JJ, Orskov C, Nielsen OV, Schwartz TW (1987) Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut

In these circumstances patients will remain at the lower dose rather than stepping up to the maintenance dose of Wegovy

doi: 10.1152/jappl.1992.72.2.549

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These pathways include the cyclic AMP-protein kinase A (cAMP-PKA) pathway, phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/Akt/mTOR) signaling, and nuclear factor kappa B (NF-B)-mediated cascades, which regulate cell proliferation, apoptosis, and migration