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In PCOS patients (42) resistant to clomiphene citrate induction, CoQ10 could induce ovulation when combined to clomiphene citrate (N=51, 65.9% ovulation/cycle) as compared to controls (N=50 patients treated with clomiphene citrate alone, 15.5% ovulation/cycle) which leads to higher pregnancy rate per patient (37.3% vs 6%)

This reduced lifespan is largely attributable to increased cardiovascular disease (Ryan 2015

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Reductive stress occurs when there is an excess of antioxidant power in the cells, which can actually interfere with normal cellular signalling

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