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This includes practicing rigorous, disciplined pacing to avoid triggering post-exertional malaise, maintaining detailed symptom tracking to identify your unique environmental and dietary triggers, and fiercely prioritizing restorative rest

Angew Chem Int Ed Engl (2015) 54(37):108337

From our perspective IGF-1, GH, and insulin conform a finely regulated axis that inform cells about the nutritional status of the organism so that they can either undergo apoptosis/senescence/quiescence or, to the contrary, grow and differentiate

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