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The phase 2 trial included adults up to age 75, and older participants responded well to the drug

as mentioned, the animal study by Zhang 2015 found reduced DNA fragmentation in sperm of GLP-1-treated mice, hinting at a protective effect on sperm DNA perhaps via less oxidative stress or inflammation

Prodigal: prokaryotic gene recognition and translation initiation site identification

doi: 10.1007/978-3-319-20013-2_3

The nausea associated with retatrutide is generally described as dose-dependent, meaning it tends to be more pronounced at higher doses and during the dose-escalation phase of treatment