These extracts caused DNA nicks, apoptosis, and cell cycle arrest in a dose- and time-dependent manner by increasing the production of reactive oxygen species (ROS) and lowering mitochondrial potential [93] possibly by blocking the Protein Kinase C (PKC) [94]
Some of these mechanisms include increasing epidermal thickness, cytokeratin in suprabasal layers of keratinocytes, normal shedding of epidermal squamous layers, DNA repair activity, apoptosis of damaged cells, enhanced activity of antioxidant enzymes and, last but not least, skin pigmentation (3, 4)
Research on human subjects or specimens collected from humans must comply with institutional ethical regulations
2021 May;42(5):441-447
Whitening and lightening of skin tone Repair of damage skin Regeneration of new cells Enhance skin texture Moisturises the skin Minimizing wrinkles and fine lines Fair and radiant skin tone Eliminate skin blemishes Lifted and tighter skin Youthful looking skin How to Use Shiro Advanced Glutathione 5000mg Whitening Injection Reconstitute the solution in the powder vial with 100ml-500ml of Saline for injection by means of a syringe with an appropriate needle through IV Remove the seal of the vial and wipe closures with disinfectant, then insert the needle of the syringe in the vial through the centre of the rubber closure and direct the flow of water toward the glass wall of the vial
