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Thus, resolving a hemostatic defect, the hallmark of which is a markedly prolonged bleeding time, BPC 157 reduced the bleeding times in the tail amputation model, heparin and partly warfarin rats, but unlike in normal rats, did not reduce bleeding time in heparin and warfarin rats when previously L-arginine or L-NAME was given

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doi: 10.3389/fphar.2025.1483548 Received 20 August 2024 Accepted 07 January 2025 Published 05 February 2025 Volume 16 - 2025 Edited by Luca Rastrelli, University of Salerno, Italy Reviewed by Ricardo Albuquerque, National University of Trujillo, Peru Minhajur Rahman, University of Chittagong, Bangladesh Tuoyi Wang, Qiqihar University, China Updates Copyright 2025 Anjum, Nasir, Naseer, Ibrahim, Rehman, Bashir and Tul Ain