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These different directions of effect between metabolic health and motivational decision-making are not necessarily in competition: instead, our results could be explained by a positive feedback loop wherein decreased motivational tendencies and a behavioural bias towards energy conservation inhibits behaviours such as physical exercise, leading to weight gain and the continued maintenance or progression of metabolic dysfunction, which due to biological interactions between metabolic and neurocognitive mechanisms, also alter cognition and worsen motivational tendencies

Hepatology 28(2):521525

After 21 days at room temperature or if the pen is ever exposed to temperatures above 86F, it should no longer be used

Use a pillbox or set an alarm on your phone if you need help remembering to take your pill

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