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Sexual Side Effects Prevalence: 40-60% of users (more pronounced in males) Onset: 1-4 hours Duration: Variable, may persist hours after injection MT-2 activates MC3R and MC4R in the hypothalamus, triggering dopaminergic pathways associated with sexual arousal (Van der Ploeg et al., 2002)

Jeevanandam J, Kiew SF, Boakye-Ansah S, Lau SY, Barhoum A, Danquah MK, Rodrigues J

Motley Rice is representing injured patients in semaglutide lawsuits against Novo Nordisk

Some take tiny portions for practical reasons, such as cutting costs

We encourage patients to stick with it through these side effects, because the long-term outcomes are generally worth the initial discomfort