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As a result, the brain receives abnormally amplified sensory information, ultimately leading to a hypersensitive pain response

well-tolerated in mice, rats, rabbits, and dogs with no serious organ toxicity.[34][35] Clinical Safety : Mild local irritation possible at injection sites, but no systemic adverse effects reported in trials.[36][37] Potential Risks : Theoretical concerns include pro-angiogenic effects potentially promoting tumor growth, though no evidence supports this in studies.[38] Long-term human data is limited, so monitoring is advised

Cree BAC, Bennett JL, Kim HJ et al (2019) Inebilizumab for the treatment of neuromyelitis optica spectrum disorder (N-MOmentum): a double-blind, randomised placebo-controlled phase 2/3 trial

Local action and protection of the intestinal barrier

"About 70% of the weight loss is fatty cells and about 30% is muscle cells