This concern comes from studies in rodents, and its not yet known if the risk is the same for humans
As the medication leaves your body, your appetite and cravings come back
That said, common clinical patterns include: Reduced hunger and cravings Smaller portion sizes Less emotional and stress eating Gradual, steady fat loss Improved blood sugar control Semaglutide tends to produce consistent, sustainable weight loss , especially for patients who combine treatment with nutrition and lifestyle support
Pairing your prefilling routine with a consistent semaglutide diet plan and paying attention to foods that support your protocol while avoiding foods that worsen side effects creates a comprehensive system where prefilling is just one element of a well-managed semaglutide routine
doi:10.1186/s12933-022-01604-7 6.Fras JP, Davies MJ, Rosenstock J, et al