does semaglutide cause pregnancy Semaglutide, Fertility & GLP-1s and Fertility - Endocrinology

This is the critical finding

Ferraro, B

Washington, DC, US

Who Is Generally Excluded FDA labels list contraindications and precautions that typically rule out or require caution with GLP-1 therapy: Personal or family history of medullary thyroid carcinoma Multiple endocrine neoplasia syndrome type 2 (MEN 2) Known hypersensitivity to the drug History of pancreatitis (caution, not absolute contraindication) Active gallbladder disease (caution) Severe gastroparesis or other significant GI motility disorders Pregnancy or planning pregnancy (discontinuation typically recommended) Type 1 diabetes (not studied for this indication) Additionally, patients with severe kidney or liver disease, those on certain medications that affect insulin or GI motility, and those with eating disorders should have careful evaluation

Most are approved to treat Type 2 diabetes, while others are specifically approved for weight loss, obstructive sleep apnea, and other uses