This is what a dysfunctional quality system looks like in practice
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These peripheral and central deficits can include severe gastrointestinal lesions, intracranial (superior sagittal sinus) hypertension, brain swelling and lesions, portal and caval hypertension, aortic hypotension, peripheral and central thrombosis, inferior caval vein and superior mesenteric vein congestion, azygos vein failure, electrocardiogram (ECG) disturbances, and heart, lung, liver, and kidney lesions (Vukojevic et al., 2018
For example, a prospective cohort study patients found that participants with higher IGF-1 levels had a 55% lower relative risk of myocardial infarction compared to those with lower levels (Macvanin et al., 2023)
Angstwurm MW et al (2007) Selenium in Intensive Care (SIC): results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock