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If approved, CagriSema would provide patients and healthcare professionals with an additional treatment option supported by results from the REDEFINE clinical program, including robust efficacy, high treatment completion rates, and a tolerability profile consistent with its underlying pharmacology

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Extracorporeal treatment for valproic acid poisoning: systematic review and recommendations from the EXTRIP workgroup

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The present review addresses this knowledge gap by identifying three key context-dependent mechanisms governing the dual role of lactate: Metabolic enzyme expression patterns, pH homeostasis capacity and antioxidant defense capabilities