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These symptoms typically occur during treatment initiation or dose escalation and usually diminish over several weeks as the body adjusts to the medication

Menge BA, Schrader H, Breuer TG et al (2009) Metabolic consequences of a 50% partial pancreatectomy in humans

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There is castration/replacement evidence that testosterone indeed drives aggression in some species, but causal evidence in humans is generally lacking and/orfor the few studies that have pharmacologically manipulated testosterone concentrationsinconsistent

Cognitive decline is not inevitable, but it is multi-factorial