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That depends on how long it takes for your body to adjust to the medication, says Carmen Fong, MD, a double board-certified general and colorectal surgeon and author of Constipation Nation

If you already take blood pressure medication, have heart disease, have kidney concerns, or experience dizziness while using tirzepatide, medical monitoring is important

Include dates, severity, and any treatments or medications used in response

The bundle pricing (from $99/mo on the 12-month plan) and microdosing option make it a distinctly different play than the three programs above

Quality matters, especially when appetite is low