All these issues can lead to irreversible damage, deterioration of visual function, loss of the eye, and in extreme cases, may even be lifethreatening
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Sodium-glucose cotransporter 2 (SGLT2) inhibitors or GLP-1 RAs are recommended as second-line treatment, and pioglitazone, DPP4 inhibitors, acarbose, or insulin as third-line treatment [5]
First, patients experience an urge to move the legs, usually accompanied by uncomfortable sensations described as crawling, tingling, burning, or aching deep within the leg muscles
Arnold, M