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In these metabolic trials, psychiatric outcomes were not pre-specified primary endpoints

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Supplementary material The Supplementary Material for this article can be found online at: References 1 AbdelkhalekA.SalemM

Therefore, for the insulin regimen subgroup analysis, the treatment policy estimand was used to reflect the effect of initiating treatment with oral semaglutide compared with initiating treatment with placebo, both potentially followed by either discontinuation of the trial product and/or initiation of rescue medication

Algunos estudios ponen de manifiesto la importancia de la dieta en la prevencin del envejecimiento