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Physiological Effects The culmination of Tirzepatide's dual agonism and unique signaling properties translates into a broad range of beneficial physiological effects that address multiple facets of metabolic disease: Pancreatic Function: Tirzepatide potently stimulates both the first-phase (rapid) and second-phase (sustained) insulin secretion from pancreatic -cells in a glucose-dependent manner

This dual benefit enhances overall health and supports better diabetes management

Koryagina NL, Saveleva EI, Khlebnikova NS, Radilov AS

J Extracell Vesicles 8(1):1629865 Whiteside TL (2016) Tumor-derived exosomes and their role in cancer progression

doi:10.1530/REP-20-0643 54