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This enzyme relies entirely on a steady supply of GSH to catalyze the reduction of hydrogen peroxide (H2O2) and lipid peroxides into water and harmless alcohols

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The biologically active form of vitamin B6, pyridoxal 5-phosphate (P5P), is used as a cofactor in hundreds of different cellular reactions.[ref] Let me hit the highlights here: Nervous system and neurotransmitters : P5P is essential in the process of synthesizing serotonin from the amino acid tryptophan