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Antioxidant use after diagnosis of head and neck squamous cell carcinoma (HNSCC): a systematic review of application during radiotherapy and in second primary Cancer prevention

upregulation of antioxidant enzymes like catalase (CAT), superoxide dismutase (SOD), glutathione reductase (GR) glutathione peroxidase (GPx), heme oxygenase, endothelial nitric oxide synthase, and other protective proteins (5)

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Avoid other actives, retinoids, acids, vitamin C, during the GHK-CU introduction period