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[25] A minimum washout period of 14 days must elapse after discontinuing an MAOI before initiating sertraline therapy, and similarly, at least 14 days must pass after stopping sertraline before starting any MAOI

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Proc Natl Acad Sci USA 94:27452750

Smokers with genetic predispositions to nicotine addiction and lower dopamine sensitivity often struggle with both continued smoking and medication side effects