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Opening at 2 mg weekly rather than 4 mg markedly softens early GI effects, and any higher weekly dose simply calls for more than one vial or a split across two sites

Recognizing when to consult a specialist is critical for addressing the issue early and preventing further progression

The fact that the lean body mass decreased from four to eight weeks in the Setria and placebo groups suggests bad experimental design (the researchers hypothesized "eating less" and "over-reaching") -- these variables should be better accounted for in a proper study

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10.1152/ajpgi.00500.2004 Am