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Amy Rothberg, an endocrinologist at the University of Michigan, says patients recruited for the Ozempic clinical trials were screened for depression, anxiety and suicidal thoughts

Muniain M, Rodrigues C, Pozuelo F, Romero A, Mata R, Perez-Venegas J, et al

It showed significant effectiveness in phase 3 trials (ATTAIN-1), reducing body weight by approximately 12.4% (about 27 pounds) at the highest dose (17.2 mg) over 72 weeks

Unlike natural GLP-1 with its 2-minute plasma half-life, GLP1-R offers sustained receptor activation enabling detailed investigation of GLP-1 pathway mechanisms across diverse physiological systems

1 Amino 5 MQ 11