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A study on glioblastoma stem cells reported that phenformin, moroxydine, proguanil and cycloguanil exerted a significant impairment of glioblastoma stem cells proliferation, invasiveness and self-renewal ( In vivo , NT1014 reduced tumor weight by 61%, whereas metformin by only 32%

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The potential benefits of CP therapy in patients with severe COVID-19 is also unclear, as patients with severe disease may have already developed high antibody titres against SARS-CoV-2 (refs

doi: 10.1007/s00262-021-02934-3 236 WangSLiFYeTWangJLyuCQingSet al

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