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Tissue-Specific Research Evidence: Translating Mechanisms to Models Gastric Mucosa: The Original Model The gastric mucosal protection model is where BPC-157 research began and where the mechanistic evidence is deepest

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The endogenous carnitine synthesis is insufficient to meet the human body need, thus, about half of the carnitine pool is absorbed from the diet

Nat Commun 11(1):1896

The profound anatomical and pathophysiological disparities between these models and human disease create a significant translational gap. Acknowledging these limitations is key to interpreting preclinical data cautiously and designing more relevant experimental paradigms