Enns, GM, Moore, T, Le, A, Atkuri, K, Shah, MK, Cusmano-Ozog, K, Niemi, AK, Cowan, TM 2014, Degree of Glutathione Deficiency and Redox Imbalance Depend on Subtype of Mitochondrial Disease and Clinical Status, The Public Library of Science One , vol
When this conversion is impaired due to reduced methylfolate, homocysteine accumulates in the blood, causing inflammation and oxidative stress in blood vessels
Therapeutic effect of adjunctive N-acetyl cysteine (NAC) on symptoms of chronic schizophrenia: A double-blind, randomized clinical trial
Glutathione Metabolism and Its Implications for Health
This strategy, explored over the last two decades, has recently been successful using GST-activated nitrogen mustard (TLK286) and GT-activated arsenic-based (GSAO and Darinaparsin) prodrugs confirming the potential of GSH-conjugates as anticancer drugs