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Obesity can cause vascular smooth muscle cell proliferation, migration, and arterial stiffness

Tirzepatide has a different side effect profile, and many people who struggled with semaglutide find tirzepatide more tolerable, though the reverse can also be true

These are active compounds

When taken concurrently, the additive effect on the cardiovascular system requires baseline and periodic monitoring of blood pressure and pulse to ensure these levels remain within a safe therapeutic range

Tirzepatide side effects The most common adverse effects of tirzepatide are gastrointestinal: nausea, vomiting, diarrhea, constipation, abdominal pain, and decreased appetite