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Ref 5: Ref 6: Ref 7: Ref 8: Ref 9: Rubino et al

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Semaglutide produces roughly twice to three times more weight loss and offers cardiovascular protection, making it the more effective choice for most patients seeking significant, sustained weight loss

Because for every ounce of fat that you burn and you will be burning fat rapidly youre gonna lose water. From dehydration, Decotiis says, feelings of hunger, fatigue and dizziness may manifest, which is not going to have a great impact on your mood, potentially. Does Ozempic make anyone else feel depressed, unmotivated and sad? asked one person in the subreddit r/OzempicForWeightLoss

On one hand, evidence points to a decline in knee replacement procedures among nonobese patients, for example