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Placebo-controlled dose-ranging phase 2 study of subcutaneously administered LHRH antagonist cetrorelix in patients with symptomatic benign prostatic hyperplasia

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While LH-RH analogs have been widely used in prostate cancer and studied in BPH treatment by reducing androgen levels, GH-RH antagonists offer a distinct mechanism by inhibiting growth factors, inflammatory pathways, and cellular signaling involved in prostate enlargement