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Hepatic cholesterol crystals and crown-like structures distinguish NASH from simple steatosis

Clinical procedures were performed at the Bastyr Center for Natural Health (Seattle, WA)

The trial found a reduction in HFH, urgent HF visits, or cardiovascular death with dapagliflozin compared to placebo (16.4% versus 19.5%

Improved Insulin Sensitivity: Enhances glucose metabolism and may support blood sugar regulation, making it a potential tool in managing metabolic syndrome and type 2 diabetes

Such sORFs produce bioactive peptides, collectively referred to as mitochondrial-derived peptides (MDPs), with broad physiological functions 13,14