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BDNF: a key factor with multipotent impact on brain signaling and synaptic plasticity

Avoid repeated freeze-thaw cycles of reconstituted solutions, as temperature fluctuations may lead to peptide degradation and reduced biological activity

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Journal of Developmental & Behavioral Pediatrics, 46 (1), e17e24

The initial interest in sirtuins followed the discovery that their activation could mimic caloric restriction, which has been shown to increase lifespan in lower organisms