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"Vitamin B12 and the risk of neural tube defects in a folic-acid-fortified population"

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Tirzepatide activates two metabolic pathways simultaneously, making it potentially more effective but also newer with less long-term safety data

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targeted therapy in RCC)by clarifying disease-specific regulatory mechanisms: PKD1 mutation-driven mitochondrial defects in ADPKD, DPP9-Nrf2-mediated sorafenib resistance in RCC, and PPARFABP1 axis dysregulation in IgA nephropathy, alongside shared core pathways (e.g., GPX4/SLC7A11 as central checkpoints)