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By increasing DHODH activity when GPX4 is inactive, CoQH2 production is significantly increased and lipid peroxidation is neutralized, thereby mitigating ferroptosis in mitochondria [70]
CAC is crucial in the control of the influx of acyl units into mitochondria and hence of FAO (Figures 2, 3)
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43 CojocaruK.-A.LuchianI.GoriucA.AntociL.-M.CiobanuC.-G.PopescuR.et al (2023)
Many patients taking GLP-1 receptor agonists such as semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and liraglutide (Saxenda, Victoza) report feeling colder than usual during treatment
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