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The mechanisms underlying the benefits of N -acetylcysteine in subjects with chronic obstructive pulmonary disease are not completely understood

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doi: 10.3390/v15071545 79 StylianouEAukrustPBendtzenKMllerFFrlandSS

Klotho is a target gene of PPAR-gamma

Depletion of ALDH2 eliminates these beneficial effects