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Patients expecting dramatic weight reduction or perfect bodies often feel disappointed despite technically successful surgery

Evidence from randomized controlled trials and meta-analyses indicates potential improvements in fasting plasma glucose, glycated hemoglobin, insulin resistance indices, and inflammatory biomarkers, although heterogeneity in formulation composition, intervention duration, dosing strategy, and background pharmacotherapy attenuates certainty of effect

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Nat Rev Dis Primers (2017) 3:17013