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10.1111/1348-0421.12175 75 NishidaA.NishinoK.OhnoM.SakaiK.OwakiY.NodaY.et al (2022)

[6] Release of GST-A1 as an indication of cellular necrosis [edit] Increases in serum and urinary GST-A1 have been found in association with hepatocyte and renal proximal tubular necrosis respectively, and have potential for monitoring injury to these tissues

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Mice subjected to 6 weeks of prolonged stress followed by 6 weeks of social isolation exhibit symptoms of depression, accompanied by elevated levels of astrocyte activation in the dorsal and ventral dentate gyrus regions of the hippocampus (Woodward et al., 2018)