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Cancer 118:45794588 Li C, Wu LE (2021) Risks and rewards of targeting NAD(+) homeostasis in the brain

Little), U01NS098969 (R.M.R.) and U01NS117836 (R.M.R.)

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Despite considerable progress in the field of psychopharmacology, traditional antidepressant therapies persistently exhibit significant shortcomings, such as delayed therapeutic onset, suboptimal rates of remission, elevated instances of partial response, and adverse side-effect profiles (2, 3)

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