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With the highest dosage of 420 mg every four weeks, the effects were even more prominent: a weight reduction of 4.9% by day 7, escalating to 14.5% by day 85

One study found that 27% of women and 19% of men on very low-calorie diets reported decreased libido, and men on an eight-week, 1,200-calorie diet experienced a 30% reduction in total testosterone levels

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However, individual tolerance varies, and some people may need less