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Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility

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Death was confirmed by observing the cessation of heartbeat and respiration, after which the animals were monitored for an additional 2 min to ensure complete demise

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2.4.1.4 Effects of ISL on liver cancer The known anticancer mechanisms of ISL involve inhibiting cell proliferation, inducing cell apoptosis and cycle arrest, and promoting oxidative stress