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For instance, increased PPP flux has been observed in cancer cells, providing metabolic advantages for their rapid proliferation and survival

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4.3 Reproduction To ensure a required gene expression pattern to support embryonic development, the maternal (oocyte) and paternal (sperm) epigenome are remodeled to reach totipotency, driving cellular differentiation toward all cell types (Ross and Sampaio, 2018), including embryonic and extraembryonic ( i.e ., placenta) cell types

doi: 10.1016/s0891-5849(02)01084-5

After dehydration with graded ethanol, tissues were embedded in paraffin, sectioned (thickness, 4 m) and subjected to hematoxylin and eosin (H&E), safranin-O-fast green and Masson staining