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Research suggests GHK-CU has a relatively short half-life, making twice-daily administration theoretically superior for sustained gene expression effects

The cumulative incidence of NAION over 36 months was significantly higher in the semaglutide group (8.9%) compared to the non-GLP-1 RA group (1.8%)

This finding may also be related to the effect of GLP-1RA on the Erk1/2 signaling pathway (97)

Both are FDA-approved for managing type 2 diabetes and have shown remarkable effectiveness for weight loss, but which one is better

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